Trends in Neurosciences
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Formation of excitation-inhibition balance: inhibition listens and changes its tune
Sep 20th 2014, 00:00, by Huizhong W. Tao, Ya-tang Li, Li I. Zhang

Recently, Xue, Atallah, and Scanziani reported that excitation/inhibition ratios across cortical pyramidal neurons are equalized by activity-dependent modulations of parvalbumin-neuron mediated feedforward inhibition. Their results raise questions about the developmental formation of this excitation-inhibition balance and the potential activity-dependent synaptic plasticity rules that mediate this process.

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