| Neuronal remodeling in retinal circuit assembly, disassembly, and reassembly Aug 22nd 2014, 00:00, by Florence D. D'Orazi, Sachihiro C. Suzuki, Rachel O. Wong The assembly of neuronal circuits during development involves cellular and molecular processes that are orchestrated at multiple levels. Component cell types need to be generated in the right numbers and positioned at their final locations. Each cell type must then elaborate axons and dendrites to connect with suitable synaptic partners, and establish the mature number, type, and distribution of synapses. Also, synaptic machinery has to be localized appropriately, and the molecular composition unique to each synapse type must be attained to ensure proper function. |
